Disease Free Margins Assessment Using Enhanced Methylene Blue Video Contact Endoscopy with SPIES Filters in Vocal Fold Malignancies
| Autor: | Mura Hainarosie, Irina Ionita, Catalina Pietrosanu, Viorel Zainea, Razvan Hainarosie |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.diagnostic_test
business.industry Materials Science (miscellaneous) Process Chemistry and Technology General Engineering Disease free General Chemistry General Medicine General Biochemistry Genetics and Molecular Biology Endoscopy chemistry.chemical_compound chemistry Materials Chemistry medicine General Pharmacology Toxicology and Pharmaceutics Nuclear medicine business Methylene blue |
| Zdroj: | Revista de Chimie. 68:1768-1770 |
| ISSN: | 2668-8212 0034-7752 |
| DOI: | 10.37358/rc.17.8.5761 |
| Popis: | Vocal fold carcinomas represent a pathology that has an important incidence. Recent studies showed that 70% of the dysplastic lesions can skip the phases of mild and severe dysplasia directly to carcinoma. For that reason early detection of a malignancy of the vocal fold is mandatory. If the lesion is discovered in an early stage it must be aggressively treated using CO2 LASER surgery and disease free margins must be obtained. Because frozen sections are not always available in all medical centers we are proposing a new protocol to assess disease free margins during CO2 LASER assisted laryngoscopy. Methylene blue contact endoscopy is not a new method, as it was introduced in laryngology by professors Oscar Diaz and Mario Andreea in 1994. We are proposing a protocol designed to assess disease free margins using an enhanced video contact endoscopy with SPIES software filters. The SPIES filters technology is a relatively new technology proposed by Karl Storz in 2013. A critical analysis of the method will be done comparing the results with paraffin histopathology exam. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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