ChemInform Abstract: Synthesis of Novel Indolizine Derivatives

Autor: D. Bigg, Bernard Bonnaud, J. F. Patoiseau
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 23
ISSN: 0931-7597
DOI: 10.1002/chin.199220160
Popis: The reaction of a number of γ-butyrolactones with azole anions is shown to give γ-substituted butanoic acids in moderate to good yields. The pyrrolyl and indolylbutanoic acids obtained underwent cyclization in a simple one-pot procedure employing ethyl chloroformate and boron trifluoride etherate. Some aspects of the chemistry of the resulting indolizin-8-ones are described.
Databáze: OpenAIRE