Abstract P5-08-17: Breast cancer in octagenerians: A community hospital experience

Autor: D Caldwell, V Gadiyaram
Rok vydání: 2017
Předmět:
Zdroj: Cancer Research. 77:P5-08
ISSN: 1538-7445
0008-5472
DOI: 10.1158/1538-7445.sabcs16-p5-08-17
Popis: Background : Breast cancer incidence increases with age. However Elderly patients are undertreated and underdiagnosed affecting their overall survival with limited availabilty of clinical trial data Patients and Methods : We used the data from our cancer registry to evaluate the cases of breast cancer diagnosed between the years 2005-2010 with follow up data available to date to examine the method of diagnosis(mammogram vs palpable abnormality ), Age at diagnosis, Stage at diagnosis, Type of surgery (BCT Vs Mastectomy ), Receptor status(ER/PR/Her 2 neu) and treatment's received ( Hormonal therapy , Radiation therapy and chemotherapy) and average survival after the diagnosis of breast cancer. Data regarding the causality of death was not readily available as part of the registry data. Results : A total of 495 breast cancer cases diagnosed in the years between 2005-2010 wee identified ., Median age at diagnosis was 85 with ages ranging from 81-102 .Out of the 495 patients 55 % were diagnosed with a mammogramand 41 % by palpable abnormality. Patients were diagnosed at Stage 0,1,2,3,4 (12%,45 %,7% ,3 %. 55% underwent Lumpectomy and 31 % underwent Mastectomy .82 % and 18 % ER negative. Her 2 data was only available in 59 patients, out of those tested only 4 Her 2 positive. , Radiation(34 %) /Chemo(6 %)/ Hormone(34%) ,Radiation/Chemo 2 % ,Radiation/Hormone 18%, Chemo/Hormon 2% , 41 % didn't proceed with any treatments.Median survival was 54 months and Average survival was 56 months. Median survival 54 months and average survival was 56 months, With 203 patients alive at the end of 5 years with mortality of about 62 %. However we do not have the data of causality of death in these patient . Comparison between Age Groups : See table below Comparision of data b/n Age groupsAge at Diagnosis80-8485-8990 +No of patients24419256Mammogram13810532Palpable Lump947924Lumpectomy1576724Mastectomy803026Average Survival in months84.54848.5 Conclusion: Even though Surgery was performed in most the patients , Only 50 % or lesser number of patients had Adjuvant treatment with Endocrine , Radiation and chemotherapy. Based on the data even though most patient were diagnosed with early stage breast cancer , had significantly poor survival with median survival of about 54 months . With Survival dramatically dropped from 84 months to 48 months in patient 85 + years of age. Citation Format: Gadiyaram V, Caldwell D. Breast cancer in octagenerians: A community hospital experience [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P5-08-17.
Databáze: OpenAIRE
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