Tissue attachment strength of prosthetic meshes used in ventral and incisional hernia repair

Autor:	R. W. Stout, D.G. Baker, K.V. Rhynes, D. Bellanger, Karl A. LeBlanc
Rok vydání:	2002
Předmět:	Tissue Adhesion biology business.industry medicine.medical_treatment Adhesion (medicine) Anatomy biology.organism_classification medicine.disease Prosthesis Abdominal wall New Zealand white rabbit medicine.anatomical_structure medicine Surgery Hernia business Surgical incision Abdominal surgery
Zdroj:	Surgical Endoscopy. 16:1542-1546
ISSN:	1432-2218 0930-2794
DOI:	10.1007/s00464-001-8271-y
Popis:	Background: Many prosthetic materials are used in incisional hernia repair, including polypropylene (PP) and expanded polytetrafluoroethylene (ePTFE). However, PP forms severe adhesions and ePTFE has raised concerns about the adequacy of tissue attachment. Methods: The early tissue attachment strength of PP and two new forms of ePTFE (DLM and DLMC) was compared in a rabbit model (n = 12) in which disks of the three meshes (n = 8 of each material) were implanted against the abdominal wall for 3 days. Results: Tensiometer testing found that DLMC mesh had significantly greater attachment strength than PP (p = 0.02). Histologic studies indicated that this was due to cellular ingrowth. Tissue adhesions were observed with all eight PP disks, one DLMC disk, and none of the DLM disks. Conclusion: Modified forms of ePTFE mesh may provide abdominal wall repairs that are as strong or stronger than those obtained with PP, with early tissue attachment and without adhesions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eb6ca9cd3cc29667f7957d29aec6624c https://doi.org/10.1007/s00464-001-8271-y Zobrazit plný text záznamu Full text from SpringerLink