| Autor: |
Alejandro J. Brenes, Jens L. Hukelmann, Laura Spinelli, Andrew J.M. Howden, Julia M. Marchingo, Linda V. Sinclair, Christina Rollings, Olivia J. James, Iain R Phair, Stephen P. Matthews, Sarah H. Ross, J. Simon C. Arthur, Mahima Swamy, David K. Finlay, Angus I. Lamond, Doreen A. Cantrell |
| Rok vydání: |
2022 |
| Popis: |
The Immunological Proteome Resource (ImmPRes;http://immpres.co.uk/) is an open access public resource integrating proteomic data generated by large-scale mass-spectrometry analysis of murine hematopoietic populations. The initial focus is T lymphocytes and how their proteomes are shaped by immune activation, environment, and intracellular signalling pathways with an aim to expand it to B cells and innate immune cells. It is a multidisciplinary effort between immunology and mass spectrometry-based labs with the objective to help define an in-depth high-quality map of immune cell proteomes. Maintaining data reproducibility and integrity are a priority within the resource, thus there is an in-depth protocols section explaining in detail the sample processing and the mass spectrometry-based analysis. ImmPRes provides open access to proteomic datasets covering a wide range of murine leukocyte populations with analysis of copy numbers per cell of > 10,000 proteins, enabling new understanding of lymphocyte phenotypes. All data is accessible via a simple graphical interface that supports easy interrogation of the data and options to download data summaries and raw data files. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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