Double DQN for Chip-Level Synthesis of Paper-Based Digital Microfluidic Biochips

Autor: Katherine Shu-Min Li, Sying-Jyan Wang, Fang-Chi Wu, Tsung-Yi Ho, Jian-De Li
Rok vydání: 2021
Předmět:
Zdroj: DATE
DOI: 10.23919/date51398.2021.9474065
Popis: Paper-based digital microfluidic biochip (PB-DMFB) technology is one of the most promising solutions in biochemical applications due to the paper substrate. The paper substrate makes PB-DMFBs more portable, cost-effective, and less dependent on manufacturing equipment. However, the single-layer paper substrate, which entangles electrodes, conductive wires, and droplet routing in the same layer, raises challenges to chip-level synthesis of PB-DMFBs. Furthermore, current design automation tools have to address various design issues including manufacturing cost, reliability, and security. Therefore, a more flexible chip-level synthesis method is necessary. In this paper, we propose the first reinforcement learning based chip-level synthesis for PB-DMFBs. Double deep Q-learning networks are adapted for the agent to select and estimate actions, and then we obtain the optimized synthesis results. Experimental results show that the proposed method is not only effective and efficient for chip-level synthesis but also scalable to reliability and security-oriented schemes.
Databáze: OpenAIRE