| Autor: |
Pei-xin Li, Hua-jun Lin, Cai-li Su, Baoyi Zhao, Wen-hao Man, Zhong-tao Zhang |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-338309/v1 |
| Popis: |
Introduction: We present the case of an intraductal papillary neoplasm of the bile duct (IPNB) accompanying a small cell neuroendocrine carcinoma. Patient concerns: A 73-year-old male Chinese patient presented with jaundice of unknown origin. A contrast-enhanced computed tomography scan revealed that the wall of the lower common bile duct was thickened and nodular, causing a narrowing in the lumen and upper common bile duct enlargement above the narrow segment. Diagnosis and interventions: The initial diagnosis based on clinical manifestations was IPNB and pancreatoduodenectomy was performed. Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia, indicating IPNB. Immunohistochemistry was positive for neuroendocrine markers indicative of infiltration and small cell neuroendocrine cancer. Outcomes: The patient died on postoperative day 138. Conclusion: This is the first reported case of its kind, as none has been reported in any published literature so far. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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