Pain control post IMRT for malignant pleural mesothelioma
| Autor: | Mohamed Amin, Mohamed Lotayef, Rabab Mohamed Gaafar, Abdelrahman Mohamed Abdelrahman, Maha Hassan Mokhtar, Sherweif Abdel Fattah |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :5420-5424 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns4.9735 |
| Popis: | Purpose: This is retrospective study-reviewing patients with unresectable pleural mesothelioma who received IMRT as part of their treatment course. This work aimed to study pain control and improvement among this group of patients. Methods and Materials: Between 2016 and 2020, 50 patients with unresectable malignant pleural mesothelioma following chemotherapy, of both sex and different age groups, were treated with pleural IMRT to the hemithorax (median dose, 46.8 Gy) at The National Cancer Institute, Cairo University. Results: Of the 30 patients, 38% had stage II, 62 % had stage III, and all received induction chemotherapy (mostly cisplatin and pemetrexed) before IMRT.Patients were evaluable at week 5 post radiotherapy, 17 patients (56.7%) had an improvement of ≥30 % while 6 patients (20 %) had < 30 % pain improvement and 7 patients (23.3%) reported no pain improvement, with overall response rate was 77 %. Conclusion: Treating malignant pleural mesothelioma patients with IMRT is a feasible treatment option with an acceptable rate of pneumonitis. |
| Databáze: | OpenAIRE |
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