| Autor: |
J. Bennedsen, S. Olesen Larsen |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Acta Pathologica Microbiologica Scandinavica Section C Immunology. :377-382 |
| ISSN: |
0304-1328 |
| Popis: |
BCG immunization schedules for the demonstration of resistance to listeriosis in C3H mice were re-evaluated in a series of experiments. A two-step procedure was found to be superior to a one-step vaccination schedule. Reactivation with BCG five days before challenge caused a significant depression of the multiplication of Listeria monocytogenes in the spleen. A saline extract of tubercle bacilli was able to reactivate the BCG immunization in the “same way, even though a transient non-immunogenic effect of the same extract was also demonstrated. In the two-step procedure the vaccination dose was found to play a minor role, whereas the reactivation was dose-dependent. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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