Efficacy and safety of two doses of Norditropin® (somatropin) in short stature due to Noonan syndrome: a 2-year randomized, double-blind, multicenter trial in Japanese patients
| Autor: | Yoshihisa Ogawa, Keiichi Ozono, Reiko Horikawa, Tsutomu Ogata, Keiji Nishijima, Yoichi Matsubara, Susumu Yokoya |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Endocrinology Diabetes and Metabolism Norditropin 030209 endocrinology & metabolism medicine.disease Short stature Gastroenterology Double blind 03 medical and health sciences Safety profile Somatropin 0302 clinical medicine Endocrinology 030225 pediatrics Multicenter trial Internal medicine medicine Noonan syndrome medicine.symptom business Adverse effect |
| Zdroj: | Endocrine Journal. 65:159-174 |
| ISSN: | 1348-4540 0918-8959 |
| DOI: | 10.1507/endocrj.ej17-0313 |
| Popis: | This randomized double-blind multicenter trial (NCT01927861) evaluated the growth-promoting effect and safety of Norditropin® (NN220; somatropin) in Japanese children with short stature due to Noonan syndrome. Prepubertal children aged 3 |
| Databáze: | OpenAIRE |
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