Use of Pharmacogenomics to Guide Proton Pump Inhibitor Therapy in Clinical Practice
| Autor: | Yan Bi, M. Caroline Burton, Fernando F. Stancampiano, Ann M. Moyer, Michael J Schuh, Dana M. Harris, Jose Valery |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Physiology business.industry Gastroenterology Pharmacogenomic Testing CYP2C19 Precision medicine Clinical Practice 03 medical and health sciences 0302 clinical medicine Transplant surgery 030220 oncology & carcinogenesis Pharmacogenomics medicine 030211 gastroenterology & hepatology Racial differences Proton pump inhibitor therapy Intensive care medicine business |
| Zdroj: | Digestive Diseases and Sciences. 66:4120-4127 |
| ISSN: | 1573-2568 0163-2116 |
| Popis: | Prescribing the right medication, at the right dose, to the right patient is the goal of every physician. Pharmacogenomic information is an emerging tool that can be used to deliver precision medicine. In this review, we discuss the pharmacogenomics of available PPIs, racial differences of CYP2C19 and how PPI pharmacogenomics affects the treatment of common gastrointestinal diseases. We also provide practical guidance on when to order pharmacogenomic testing, which test to order, and how to modify treatment based on published guidelines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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