Association of cognitive function with cardiovascular risk factors in middle age individuals

Autor: E. L. Sanez, Evgeny Shlyakhto, K. I. Vanaeva, V. I. Kirillova, I. B. Zueva, V. R. Piotrovskaya, E. L. Genikhovich
Rok vydání: 2011
Předmět:
Zdroj: "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 17:432-440
ISSN: 2411-8524
1607-419X
DOI: 10.18705/1607-419x-2011-17-5-432-440
Popis: Objective. To find the association between cognitive function and cardiovascular risk factors and to develop statistic model. Results. Our study demonstrated that cognitive dysfunction is more profound in middle-aged patients with metabolic syndrome (MS) compared to the individuals with single risk factors without MS. Multiple regression analysis defined glucose (β = 0,0114) and systolic blood pressure (SBP) (β = -0,212) to be factors related with MMSE-test results. When glucose level was excluded from the model, the following factors were shown to be significant: SBP (β = -0,202), age (β = -0,093), operative memory (β = -0,169), total cholesterol level (β = -0,065), therapy by calcium antagonist (β = 0,082), obesity (β = 0,06), R = 92 %.
Databáze: OpenAIRE