Association of cognitive function with cardiovascular risk factors in middle age individuals
Autor: | E. L. Sanez, Evgeny Shlyakhto, K. I. Vanaeva, V. I. Kirillova, I. B. Zueva, V. R. Piotrovskaya, E. L. Genikhovich |
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Rok vydání: | 2011 |
Předmět: | |
Zdroj: | "Arterial’naya Gipertenziya" ("Arterial Hypertension"). 17:432-440 |
ISSN: | 2411-8524 1607-419X |
DOI: | 10.18705/1607-419x-2011-17-5-432-440 |
Popis: | Objective. To find the association between cognitive function and cardiovascular risk factors and to develop statistic model. Results. Our study demonstrated that cognitive dysfunction is more profound in middle-aged patients with metabolic syndrome (MS) compared to the individuals with single risk factors without MS. Multiple regression analysis defined glucose (β = 0,0114) and systolic blood pressure (SBP) (β = -0,212) to be factors related with MMSE-test results. When glucose level was excluded from the model, the following factors were shown to be significant: SBP (β = -0,202), age (β = -0,093), operative memory (β = -0,169), total cholesterol level (β = -0,065), therapy by calcium antagonist (β = 0,082), obesity (β = 0,06), R = 92 %. |
Databáze: | OpenAIRE |
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