Heparin-Induced Thrombocytopenia (HIT): A Case Study
| Autor: | Catherine E. Newkirk |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test biology business.industry General Medicine Heparin medicine.disease Thrombosis Gastroenterology Asymptomatic General Biochemistry Genetics and Molecular Biology Immunoglobulin G Direct thrombin inhibitor Internal medicine Heparin-induced thrombocytopenia biology.protein Medicine medicine.symptom business Platelet factor 4 Partial thromboplastin time medicine.drug |
| Zdroj: | American Society for Clinical Laboratory Science. 23:5-11 |
| ISSN: | 1945-3574 0894-959X |
| DOI: | 10.29074/ascls.23.1.5 |
| Popis: | Heparin-induced thrombocytopenia (HIT) ranges from an asymptomatic reaction to heparin with a transient mild thrombocytopenia (HIT I) to a life- and limb-threatening immunological reaction, heparin-induced thrombocytopenia with thrombosis (HITT or HIT II). HITT can occur in patients with any heparin exposure and must be recognized and treated quickly and appropriately to prevent symptomatic and/or fatal thrombosis. HIT will be discussed using a case study approach. ABBREVIATIONS:APTT = activated partial thromboplastin time; AT = anti-thrombin; 14C = carbon-14; CT = computerized topography; DTI = direct thrombin inhibitor; Fc = fragment crystallizable; FDA = Food and Drug Administration; HIPA = heparin-induced platelet aggregation; HIT = heparin-induced thrombocytopenia; HITT = heparin-induced thrombocytopenia with thrombosis; IgG = immunoglobulin G; INR = international normalized ratio; IU/ml = international units per milliliter; IV = intravenous; LMWH = low-molecular-weight heparin; PF4 = platelet factor 4; RBC = red blood cell; SC = subcutaneous; SRA = serotonin release assay; UFH = unfractionated heparin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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