An integrated lobule-mimetic liver chip for testing hepatotoxicity

Autor:	V. P. Srinivasu, Y. J. Chu, S. Shilpa, Rongshun Chen, T. H. Punde, Cheng-Hsien Liu, Shih Mo Yang
Rok vydání:	2011
Předmět:	Drug business.industry media_common.quotation_subject Diagnostic test Pharmacology Cell patterning Bioinformatics Medical care In vivo Medicine Personalized medicine business Drug toxicity media_common
Zdroj:	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference.
DOI:	10.1109/transducers.2011.5969388
Popis:	The current trend in personalized healthcare shows that medical care is becoming as individualized as possible. The goal is not only to provide customized diagnostic tests but also to target medicines and dosages more precisely and safely to each patient. Here in this article we report an integrated drug testing device based on lobule-mimetic liver pattern for testing in vitro drug toxicity. We aimed at achieving customized diagnostic tests by reconstructing and mimicking a liver pattern in vitro for predicting the in vivo drug hepatotoxicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::eb2a2454e5dc5f4bf063ad57780550eb https://doi.org/10.1109/transducers.2011.5969388 Zobrazit plný text záznamu