The effect of blending of extracts of Sudanese Adansonia digitata and Tamarindus indica on their antioxidant, anti-inflammatory and antimicrobial activities
| Autor: | Mawa Ibrahim Alnour, Saad Mohamed Hussein Ayoub, Shimaa Abdel Rahman Ahmed, Alaa Abdulmoneim Mohamed, Kowther Isam Eldein, Ayat Ahmed Alrasheid, Einas Gamal Mohieldin, Marvit Osman Widdatallh, Layla Fathi Yassin, Sahar Hussein Eltilib |
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| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Antioxidant biology Traditional medicine Chemistry DPPH medicine.drug_class medicine.medical_treatment fungi food and beverages Glycoside biology.organism_classification Antimicrobial complex mixtures Anti-inflammatory chemistry.chemical_compound Phytochemical visual_art Drug Discovery medicine visual_art.visual_art_medium Bark Adansonia digitata |
| Zdroj: | Journal of Pharmacognosy and Phytotherapy. 11:28-34 |
| ISSN: | 2141-2502 |
| DOI: | 10.5897/jpp2019.0537 |
| Popis: | Adansonia digitata (Bombacaceae) and Tamarindus indica (Fabaceae) are the most popular herbal products in Sudan; they are used as food ingredients and in traditional treatments of various diseases. The aim of this study is to investigate phytochemical contents, antioxidant, anti-inflammatory and antimicrobial activities of plants fruit, leaf and bark ethanolic extracts. The phytochemical screening of different extracts revealed the presence of alkaloids, flavonoids, sterols/triterpens, tannins, saponins, coumarins, glycosides, reducing sugar, lignin and carbohydrates. The results indicate that all the extracts have reducing power DPPH radical scavenging abilities. The highest antioxidant activity showed in A. digitata parts. The fruit extracts of both plants showed the highest antioxidant activity (84.07 and 83.98% for A. digitata and T. indica, respectively). The in vitro anti-inflammatory effects have been studied by human albumin denaturation, and both plant extracts showed remarkable activity. Leaf extracts showed highest anti-inflammatory activity (76.714, 62 and 82.71% for A. digitata, T. indica and mixture of both respectively). The results of antimicrobial activity showed the effectiveness of mixture extracts against tested standard pathogens. Fruit mixtures showed the highest activity against B. subtilis (19 mm), S. aureus (35 mm) and S. typhi (21 mm), while the mixture of bark extracts showed the highest activity against E. coli (19 mm). It is noteworthy that higher antioxidant, anti-inflammatory and antimicrobial activities have been observed by blends in the ratio 1:1 of fruit, leaf and bark extracts of both plants. Key words: Adansonia digitata, Tamarindus indica, antioxidant, anti-inflammatory, antimicrobial, combination. |
| Databáze: | OpenAIRE |
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