Isolation and Characterization of Hepatoprotective Anthraquinone Derivatives from Cucumis bisexualis

Autor: Qinge Ma, Rongrui Wei
Rok vydání: 2021
Předmět:
Zdroj: Chemistry of Natural Compounds. 57:627-630
ISSN: 1573-8388
0009-3130
DOI: 10.1007/s10600-021-03437-4
Popis: A new anthraquinone, named 1,3-dihydroxy-2-methylene-(1′-isopentyloxy)-6-methoxymethyl-8-(6′′,7′′,8′′- trihydroxyphenylketonyl)-9,10-anthraquinone (1), and nine known anthraquinone derivatives (2–10), were isolated from Cucumis bisexualis for the first time. Compounds 1–10 were evaluated for their hepatoprotective activity in human L-O2 cells compared with the positive control bifendatatum. Among them, compounds 1, 3, and 8 exhibited moderate hepatoprotective activity in the proliferation of L-O2 cells.
Databáze: OpenAIRE