Organic electrochemical techniques having potential clinical application
| Autor: | Richard A. Durst, K.A. Bunding, William A. MacCrehan, William T. Yap, Mary Lou Fultz, Elmo A. Blubaugh |
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| Rok vydání: | 1982 |
| Předmět: |
chemistry.chemical_classification
Biochemistry (medical) Clinical Biochemistry Inorganic chemistry Nanotechnology Polymer Electrochemistry Redox Metal symbols.namesake chemistry.chemical_compound chemistry visual_art Electrode visual_art.visual_art_medium symbols Photocatalysis Organomercury Raman spectroscopy |
| Zdroj: | Clinical Chemistry. 28:1922-1930 |
| ISSN: | 1530-8561 0009-9147 |
| DOI: | 10.1093/clinchem/28.9.1922 |
| Popis: | The Organic Electrochemistry Group at the National Bureau of Standards is pursuing several avenues of research of potential application to problems of clinical chemists. With one development, electrochemical detectors for liquid chromatography, organomercury species can be determined in biological tissues and other matrices. Spectroelectrochemistry is being used to characterize the redox behavior of metal complexes of bleomycin, an antitumor drug. Chemically modified electrodes are being developed as selective electrocatalytic sensors for organohalogen compounds and may lead to new sensors for clinically important analytes. Surface-enhanced Raman spectroscopy is helping characterize the polymer films used to modify the electrode surfaces. Another sensor is being developed for the detection of carboxylic acids: after the photocatalytic oxidation of the acids at a semiconductor electrode, the carbon dioxide produced is subsequently determined with a flow-through gas-sensing electrode. Finally, mathematical modeling may provide a better understanding of the fundamental processes involved in several of the above techniques. |
| Databáze: | OpenAIRE |
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