Erythrocyte zinc protoporphyrin testing in pregnancy

Autor: Jan Lindemans, Mart M. A. C. Langenhuijsen, Else J. Harthoorn-Lasthuizen
Rok vydání: 2000
Předmět:
Zdroj: Acta Obstetricia et Gynecologica Scandinavica. 79:660-666
ISSN: 0001-6349
Popis: Background. To compare the usefulness of serum ferritin, hemoglobin and erythrocyte zinc protoporphyrin estimations as indicators of the need of iron supplementation in pregnancy. Methods. In 97 healthy pregnant women serum ferritin, hemoglobin and erythrocyte zinc protoporphyrin concentrations were measured at each trimester period. Iron supplementation was prescribed at hemoglobin values below 113 g/L. Results. Neither in the first nor in the second trimester differences in serum ferritin and erythrocyte zinc protoporphyrin values have been found between women who got iron therapy prescribed and women who did not get iron therapy, whereas already in the first trimester hemoglobin values were lower in the group that got iron therapy. These results indicate that hemodilution rather than iron deficiency determined which women got iron therapy. In the third trimester 14 out of 80 women without iron supplementation had depleted iron stores and a significant erythrocyte zinc protoporphyrin increase, indicatin...
Databáze: OpenAIRE