| Autor: |
David C. O. Pickard, Irving J. Bigio, Stephen G. Bown, Laurence B. Lovat, Paul M. Ripley, Marco Novelli |
| Rok vydání: |
2001 |
| Zdroj: |
Diagnostic Optical Spectroscopy in Biomedicine. |
| Popis: |
Barrett’s oesophagus is an increasingly common pre-cancerous condition, which occurs in patients suffering from acid reflux into their gullet. Biopsies must be taken from patients diagnosed with this condition regularly to pick up signs of pre-cancerous changes. Elastic scattering spectroscopy offers the possibility of distinguishing between benign and pre-cancerous changes in the lower oesophagus with a relatively simple optical measurement. This ‘optical biopsy’ is correlated with a conventional histopathological specimen obtained at the same point. It is shown that to a relatively high degree of sensitivity and specificity it is possible to distinguish between pre-malignant patches, benign lesions and normal tissue. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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