Diagnostic Dilemma in Cytologic Features of Micropapillary Carcinoma of the Breast
| Autor: | Esra Canan Kelten, Metin Akbulut, S. Ender Duzcan |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Pathology Histology Axillary lymph nodes Psammoma body medicine.diagnostic_test business.industry Mammary gland Anatomical pathology General Medicine medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure Giant cell Biopsy Carcinoma Medicine business Breast carcinoma |
| Zdroj: | Acta Cytologica. 53:463-466 |
| ISSN: | 1938-2650 0001-5547 |
| Popis: | Background Invasive micropapillary carcinoma (IMPC) is a rare type of breast carcinoma with unique mophologic features and high frequency of axillary lymph node metastasis. Recognizing the IMPC on cytology makes it possible to identify a group of patients with a poor prognosis and may alter the adjuvant treatment. Cases We reviewed the cytologic features of a 2 IMPC cases 50-year-old women. Both cases included conventional findings of IMPC, such as increased cellularity, cell clusters with angular and papillary configuration without a fibrovascular core, tumor clusters showing an "inside-out" pattern and the presence of single discohesive cells. Of interest, both cases included a few malignant-appearing multinucleated giant cells. The slides of 1 case were included a little mucin in the background of tumor diathesis. There were no psammoma bodies in the smears. Conclusion The cytologic features of IMPC are unique and should be recognized because of its' tendency to infiltrate the axillary lymph nodes. In addition to well-known cytologic features of IMPC, multinucleated giant cells and a scanty amount of mucin should also alert the cytopathologist to the possibility of IMPC. |
| Databáze: | OpenAIRE |
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