Allele Frequency of Apolipoprotein Gene Polymorphisms and Association between Genotype and Serum Lipid and Apolipoprotein Levels
| Autor: | M Mostafa Zaman, Nobuo Yoshiike, Hiroko Iwaoka, Tetsuji Yokoyama, Masako Iwaya, Michiko Sugiyama, Hao Chen, Yasuhiro Matsumura, Chigusa Date, Takeo Nakayama, Momoko Yamaguchi, Shinji Ikemoto, Mitsuru Tsuchida, Heizo Tanaka, Hiroshige Itakura, Fukue Seino |
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| Rok vydání: | 1995 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Apolipoprotein B biology Epidemiology business.industry Population Blood lipids General Medicine Endocrinology Internal medicine Genotype biology.protein Medicine lipids (amino acids peptides and proteins) Restriction fragment length polymorphism education business Gene Allele frequency Apolipoprotein gene |
| Zdroj: | Journal of Epidemiology. 5:141-151 |
| ISSN: | 0917-5040 |
| Popis: | The rare allele frequency of the restriction fragment length polymorphism (RFLP) with Xba I (X+) at the apolipoprotein B (apo B) gene locus was 0.041 in men and 0.026 in women in H-Y district, Shiso County, Hyogo Prefecture, Japan : EcoR I at apo B gene (E-)=0.073 and 0.076, Msp I at apo Al-CIII gene (M-)=0.423 and 0.430, and Sac I at apo Al-CIII gene (S+)= 0.309 and 0.349. There was no marked ageor sex-difference in the frequencies. The frequencies of X+ and Ewere lower and those of S+ and Mwere higher in H-Y district than in Caucasian populations. In this population, according to the ANOVAs, the genotype for EcoR I was significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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