Effect of Vitamin E on the Urea Cycle Enzymes, Ornithine-keto
| Autor: | Koichi Shimbayashi, Shigemi Shoya |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Vitamin
medicine.medical_specialty Chemistry Vitamin E medicine.medical_treatment Ornithine transcarbamylase Carbamyl Phosphate Ornithine General Biochemistry Genetics and Molecular Biology Excretion chemistry.chemical_compound Ammonia Endocrinology Internal medicine medicine Urea General Agricultural and Biological Sciences |
| Zdroj: | Agricultural and Biological Chemistry. 35:983-988 |
| ISSN: | 1881-1280 0002-1369 |
| DOI: | 10.1271/bbb1961.35.983 |
| Popis: | Albino female rats were fed for 4 to 6 months on either a vitamin E-supplemented or on a vitamin E-unsupplemented diet. Of the urea cycle enzyme activities, carbamyl phosphate synthetase and ornithine transcarbamylase were significantly higher in the vitamin E-supplemented group than in the vitamin E-unsupplemented one. Reversely, the activity of ornithine-keto acid trans-aminase was lower in the former group. Urea level in the serum and liver was lower in the vitamin E-supplemented group, but urea excretion was accelerated in this group. Activity of isocitric dehydrogenase was significantly higher in the vitamin E-supple-mented group. From these results, it is suggested that vitamin E is efficient for the de-toxication of ammonia in the animal body. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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