Brachytherapy in Hepatobiliary Malignancies

Autor: Andrew S. Kennedy, Subir Nag, L. Matthew Scala
Rok vydání: 2014
Předmět:
Zdroj: Biliary Tract and Gallbladder Cancer ISBN: 9783642405570
DOI: 10.1007/978-3-642-40558-7_20
Popis: Brachytherapy (placement of radioactive material inside or close to tumors) is a very useful modality in the treatment of unresectable liver tumors. Solitary or a limited number of localized tumors can be treated with interstitial permanent 125I seeds, HDR brachytherapy, or intraluminal 192Ir to the unresected tumor or to the tumor bed after surgical resection. Diffuse or multiple primary or metastatic liver tumors can be palliated with 90Y glass or resin microsphere radioembolization. These benefits are more when the radioembolization is done early in the treatment program or combined with appropriate chemotherapy. The role of these therapies must be investigated further in controlled clinical trials to integrate and quantify the benefit when combined with other therapies.
Databáze: OpenAIRE