| Autor: |
E. Vallvé Alcón, JM Guiu Segura, I. Cardona Pacual, J. Monterde Junyent, D. Campany Herrero |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Farmacia Hospitalaria. 35:23-27 |
| ISSN: |
1130-6343 |
| DOI: |
10.1016/j.farma.2010.05.002 |
| Popis: |
Objective: Specific immunoglobulin against cytomegalovirus has demonstrated its effectiveness in preventing and treating infections in solid organ transplantation. Several studies indicate that non-specific immunoglobulin is just as effective. This study aims to determine anti-cytomegalovirus immunoglobulin titres from one of the non-specific immunoglobulin presentations authorised in Spain. Method: This was an observational study, in which we analysed the anti-cytomegalovirus antibody titres from different batches of Flebogamma® 5% 5g used at the Hospital Universitari Vall d’Hebron during 2008 and 2009. Results: We analysed 27 batches, which included 18,944 vials of Flebogamma® 5%. Depending on the origin, the median concentration of anti-cytomegalovirus immunoglobulin was 28 PEIU/ ml and 22 PEI-U/ml per vial of North American and Spanish origin, respectively (CI 95% for the difference of the medians 5 to 6 PEI-U/ml; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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