Chemical Constituents of Callicarpa giraldii and Their Anti-Inflammatory Activity
| Autor: | Zhong-Han Wu, Fan Xu, Qiao-Qi Yi, Hong-Gang Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pharmacology
Phytochemistry Traditional medicine biology medicine.drug_class Verbenaceae FAMILY VERBENACEAE Plant Science General Medicine Traditional Chinese medicine biology.organism_classification Callicarpa giraldii Anti-inflammatory Complementary and alternative medicine Chemical constituents Drug Discovery medicine |
| Zdroj: | Natural Product Communications. 16:1934578X2110518 |
| ISSN: | 1555-9475 1934-578X |
| DOI: | 10.1177/1934578x211051801 |
| Popis: | Callicarpa giraldii (family Verbenaceae) has many medical properties and is commonly used in traditional Chinese medicine. However, its chemical constituents have not been investigated. In this study, nine compounds present in the leaves and stems were isolated and characterized. These were negundonorin B (1), lupeol (2), erythrodiol (3), isoacteoside (4), forsythoside B (5), dibutyl phthalate (6), verbascoside (7), poliumoside (8), and 3-methoxy-4-hydroxybenzaldehyde (9). The structures were identified by comparison of their NMR data with those reported in the literature. The anti-inflammatory effects of compounds 1-6 were tested on lipopolysaccharide-stimulated RAW264.7 macrophages. Several compounds showed significant ( p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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