Simultaneous acquisition of vibration and diffusion by multifrequency diffusion tensor imaging-magnetic resonance elastography (mDTI-MRE)
| Autor: | Dieter Klatt, Shujun Lin, Richard Magin, Aaron T. Anderson, Bradley P. Sutton |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | The Journal of the Acoustical Society of America. 153:A311-A311 |
| ISSN: | 1520-8524 0001-4966 |
| Popis: | Magnetic Resonance Elastography (MRE) and Diffusion Tensor Imaging (DTI) are MRI techniques that provide complementary diagnostic information and utilize motion-sensitive magnetic field gradients. In MRE, tissue vibrations are encoded into the MRI signal phase, while in DTI the diffusive motion of water molecules is assessed by means of the MRI signal magnitude. Careful consideration of the motion-encoding gradient timing conditions and the mechanical frequencies allows the simultaneous acquisition of vibration and diffusion data without observable mutual interferences. We propose a multifrequency Diffusion Tensor Imaging-Magnetic Resonance Elastography (mDTI-MRE) protocol that measures the diffusive behavior along 24 directions and the full 3D displacement field at two mechanical frequencies. Using this method, mDTI-MRE provides information about the mechanical wave field and about a preferred direction, which may facilitate the accurate mechanical characterization of anisotropic biological tissues, such as brain white matter and skeletal muscle. |
| Databáze: | OpenAIRE |
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