Ocena przydatności skal APACHE II, SAPS II i SOFA jako czynników rokowniczych u chorych ze schorzeniami rozrostowymi układu krwiotwórczego leczonych na oddziale anestezjologii i intensywnej terapii
Autor: | Maria Wujtewicz, Magdalena A. Wujtewicz, Radosław Owczuk, Wioletta Sawicka |
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Rok vydání: | 2014 |
Předmět: |
Mean arterial pressure
medicine.medical_specialty Multivariate analysis APACHE II business.industry Acute kidney injury General Medicine Critical Care and Intensive Care Medicine Logistic regression medicine.disease Intensive care unit law.invention Anesthesiology and Pain Medicine law SAPS II Internal medicine Medicine Risk factor business Intensive care medicine |
Zdroj: | Anestezjologia Intensywna Terapia. 46:166-170 |
ISSN: | 1731-2515 1642-5758 |
Popis: | BACKGROUND: Cancer-related mortality remains the second most common cause of death in Poland. In many cases, the occurrence of treatment-related complications requires admission to the intensive care unit (ICU). The aim of this study was to assess the clinical application of the APACHE II, SAPS II and SOFA scales to evaluate the risk of death in patients with haematological malignancies treated in the ICU. METHODS: This study’s analysis included 99 patients, who were each assigned to one of the following two groups: surviving patients who were discharged from the ICU (n = 24); and patients who died in the ICU (n = 75). Analysis was performed using demographic, clinical and laboratory data obtained during the patient’s admission to the ICU and also during the first 24 hours of intensive therapy. Patient assessment was performed using the APACHE II, SAPS II and SOFA scoring systems as well as other clinical variables. RESULTS: Univariate logistic regression identified the following risk factors of death in patients with haematological malignancies: systolic ( P = 0.006), diastolic ( P = 0.01) and mean arterial pressure values ( P = 0.009); occurrence of acute kidney injury; neutrophil ( P = 0.009) and platelet count in the peripheral blood ( P = 0.001); and the SAPS II ( P = 0.00005), SOFA ( P = 0.00009) and APACHE II ( P = 0.0007) scores. SAPS II score was the only independent risk factor of patient death in multivariate analysis ( P = 0.0004; unitary OR 1.052 [95% CI: 1.022–1.082]). CONCLUSION: Of all the applied patient assessment scales, only the SAPS II score was found to be useful in subjects with haematological malignancies hospitalised in the ICU. |
Databáze: | OpenAIRE |
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