| Autor: |
Christopher Su, Samuel M. Rubinstein, Michael A. Thompson, Clara Hwang, Elizabeth A. Griffiths, Elizabeth Robilotti, Michael J. Joyner, Peter Paul Yu, Zoey Xie, Elizabeth Marie Wulff-Burchfield, Toni K. Choueiri, Jonathon W. Senefeld, Covid, Vadim S. Koshkin, Daniel Blake Flora, Sanjay Mishra, Esperanza B. Papadopoulos, Jeremy L. Warner, Dimpy P. Shah, Pankil Shah, Jeffrey P. Henderson, Anthony P. Gulati |
| Rok vydání: |
2021 |
| Předmět: |
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| Popis: |
SummaryConvalescent plasma may benefit immunocompromised individuals with COVID-19, including those with hematologic malignancy. We evaluated the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic malignancy and COVID-19 from a multi-institutional cohort. 143 treated patients were compared to 823 untreated controls. After adjustment for potential confounding factors, convalescent plasma treatment was associated with improved 30-day mortality (hazard ratio, 0.60; 95% CI, 0.37-0.97). This association remained significant after propensity-score matching (hazard ratio, 0.52; 95% CI, 0.29-0.92). These findings suggest a potential survival benefit in the administration of convalescent plasma to patients with hematologic malignancy and COVID-19. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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