1H, 13C, and 15N NMR assignments of a Drosophila Hedgehog autoprocessing domain

Autor:	Marlene Belfort, Zhenming Du, Brian P. Callahan, Jian Xie, Chunyu Wang
Rok vydání:	2013
Předmět:	biology Hh signaling pathway biology.organism_classification medicine.disease Biochemistry Holoprosencephaly Structural Biology medicine Drosophila (subgenus) Drosophila melanogaster Signal transduction Hedgehog Drosophila Protein
Zdroj:	Biomolecular NMR Assignments. 8:279-281
ISSN:	1874-270X 1874-2718
DOI:	10.1007/s12104-013-9500-8
Popis:	The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [13C, 15N]-labeled and [2H, 13C, 15N])-labeled proteins.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ea465f1bf8bb18e52eb494a716c37900 https://doi.org/10.1007/s12104-013-9500-8 Zobrazit plný text záznamu Full text from SpringerLink