Synthesis of polyester dendrimers and dendrons starting from Michael reaction of acrylates with 3-hydroxyacetophenone

Autor:	Kentaro Yamaguchi, Yuuki Hirayama, Yohko Sakamoto, Michiko Iwamura, Shigeru Sakamoto
Rok vydání:	2005
Předmět:	Acrylate Decarboxylation Organic Chemistry Sequence (biology) Biochemistry Polyester chemistry.chemical_compound chemistry Hydrogenolysis Dendrimer Drug Discovery Polymer chemistry 3-Hydroxyacetophenone Michael reaction
Zdroj:	Tetrahedron Letters. 46:1027-1030
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.12.004
Popis:	A new AB 2 type building block for synthesis of dendritic compounds is made starting from Michael addition of 2 equiv of 3-hydroxyacetophenone to acrylate, followed by decarboxylation and deprotection of either carboxyl or hydroxyl protecting groups. [G1]–[G4] dendrons and [G2] dendrimer were synthesized by the reiterative [hydrogenolysis then DCC/DPTS coupling] sequence using a combination of convergent and divergent growth methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ea3e4901abd8ff5adaf0b89356da3e2d https://doi.org/10.1016/j.tetlet.2004.12.004 Zobrazit plný text záznamu Full Text from ScienceDirect