Selective deprotection of esters using magnesium and methanol

Autor:	Yao-Chang Xu, Clint Walker, Elaine Lebeau
Rok vydání:	1994
Předmět:	chemistry.chemical_classification Magnesium education Organic Chemistry chemistry.chemical_element Alcohol Biochemistry humanities chemistry.chemical_compound chemistry Reagent Drug Discovery Organic chemistry Reactivity (chemistry) Methanol Selectivity Alkyl Bond cleavage
Zdroj:	Tetrahedron Letters. 35:6207-6210
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)73392-2
Popis:	The use of magnesium metal in methanol for the deprotection of alkyl esters is described. This mild reagent also provides good to excellent selectivity to cleave different esters. The order of the reactivity of this reagent towards acyl cleavages was found to be: p-nitrobenzoate > acetate > benzoate > pivaloate > trifluroacetamide.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ea23cdf502047f53b80eb14adce04a95 https://doi.org/10.1016/s0040-4039(00)73392-2 Zobrazit plný text záznamu