Variation in palliative care of esophageal cancer in clinical practice: factors associated with treatment decisions

Autor: Mariëlle J. F. Meijnen-Bult, Peter D. Siersema, Itta M. Minderhoud, Menno A. Brink, Martijn G.H. van Oijen, Boudewijn C. A. J. Loffeld, Jorrit L. Opstelten, Laetitia R H de Wijkerslooth, Marc A. M. T. Verhagen, Max Leenders, Dirk Jan Bac
Rok vydání: 2016
Předmět:
Zdroj: Diseases of the Esophagus.
ISSN: 1120-8694
DOI: 10.1111/dote.12478
Popis: Various treatments are available for the palliation of esophageal cancer, but the optimal therapeutic approach is unclear. This study aimed to assess the palliative treatment modalities used in patients with inoperable esophageal cancer and to identify factors associated with treatment decisions. A population-based, retrospective cohort study was conducted using data from the nationwide Netherlands Cancer Registry and medical records of seven participating hospitals. Patients diagnosed with stage III-IV inoperable esophageal or gastric cardia cancer in the central part of the Netherlands between 2001 and 2010 were included. Logistic regression analyses were performed to identify determinants of treatment choices. In total, 736 patients were initially treated with best supportive care (21%), stent placement (19%), chemotherapy (18%), external beam radiotherapy (EBRT) (16%), brachytherapy (6%), a combination of EBRT and brachytherapy (6%), a combination of chemotherapy and EBRT (5%) or another treatment (9%). The palliative approach varied for disease stage (P
Databáze: OpenAIRE
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