Effect of advancing maternal age on some histomorphological characteristics and other parameters of the offspring of wistar rats

Autor: Ohunene Makoju Avidime, O. Olabiyi, Oshiozokhai Eboetse Yama, Timothy Danboyi, T.O. Kusemiju, Anthony Donatus Teru Goj, AA Aladejare
Rok vydání: 2020
Předmět:
Zdroj: Nigerian Journal of Experimental and Clinical Biosciences. 8:71
ISSN: 2348-053X
DOI: 10.4103/njecp.njecp_12_20
Popis: Background: The average age of mothers at the time of first childbirth has been increasing over the past decades. Delayed motherhood comes with several adverse outcomes. Objective: We investigated the effect of advancing maternal age on some histomorphological parameters in the litters of female Wistar rats. Materials and Methods: Twenty-seven female rats (11–40 weeks old) were divided into three groups (young-, mid-, and old aged) of 9 rats each and mated with 12 male rats. The morphological parameters of the litters were obtained and a classic maze task was performed. Data were analyzed using the Statistical Package for the Social Sciences version 23 and values at P
Databáze: OpenAIRE