Design of Binary Solvent Systems for Separation of Protected Oligo-Peptides in Silica Gel Liquid Chromatography

Autor:	Akira Dobashi, Akiko Ohsawa, Shoji Hara
Rok vydání:	1981
Předmět:	chemistry.chemical_classification Solvent system chemistry.chemical_compound Chromatography Column chromatography Chemistry Silica gel Phase (matter) Molecular Medicine Kovats retention index Binary number Peptide Quantitative correlation
Zdroj:	Journal of Liquid Chromatography. 4:409-423
ISSN:	0148-3919
DOI:	10.1080/01483918108059945
Popis:	In order to adjust the binary mobile phase for the separation of protected oligo-peptides, a systematic investigation of the retention behaviour on silica gel columns was carried out using seven peptide derivatives. Quantitative correlation between the capacity ratios of solvent systems using various concentrations of the stronger eluent was determined. The strengths and selectivities of fourteen binary systems were discussed on the basis of their retention indices. The design of equi-eluotropic binary systems containing these stronger components is presented.
Databáze:	OpenAIRE
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