Research of the pharmacological activity of capsules diaplant

Autor: R. Fares, L. A. Bobrytska, S. M. Drogovoz, N .V. Popova, O. S. Shpychak, V. I. Hrytsenko, T. I. Ivko, A. V. Kononenko
Rok vydání: 2017
Předmět:
Zdroj: Likarska sprava. :144-148
ISSN: 2706-8803
1019-5297
DOI: 10.31640/ls-2017-8-22
Popis: We developed the new сomplex drug diaplant in capsules for pharmacotherapy of acute intestinal infections. Diaplant consist of the nifuroxazide 200 mg and pantaglucidum 200 mg (leaf extract of Plantago major). Antiexudative activity of diaplant was established on the model of carrageenan edema. A comparative drug for the dynamics of antiexudative activity was sodium diclofenac in tablets («Novartis pharma», Sweden). As a result of the experiment, the maximum activity was on the third hour and was 43.1 % in diaplant, and was 64.4 % for sodium diclofenac. Spasmolytic activity of diaplant was studied by the method of «carbon labels». It has been found the identity of indicators for capsules diaplant with comparative drug plantaglucid (Zdorovye, Ukraine).
Databáze: OpenAIRE