Rhodium‐Catalyzed Enantioselective Conjugate Addition of Arylboronic Acids to Dihydronitronaphthalenes

Autor:	Amit Ghosh, Rajesh Malhotra, Tushar K. Dey, Saumen Hajra, Swarup Dutta, Shantanu Dutta, Subho Roy, Rajib Ghosh, Sagar Chakrabarti, Sonika Asijaa, Sourav Basu
Rok vydání:	2012
Předmět:	Agonist Phosphoramidite Chemistry medicine.drug_class Ligand Enantioselective synthesis chemistry.chemical_element General Chemistry Combinatorial chemistry Dihydrexidine Catalysis Rhodium medicine Organic chemistry medicine.drug Conjugate
Zdroj:	Advanced Synthesis & Catalysis. 354:2433-2437
ISSN:	1615-4169 1615-4150
DOI:	10.1002/adsc.201200241
Popis:	A highly enantioselective (up to 91% ee) rhodium-catalyzed asymmetric addition of arylboronic acids has been achieved leading to the challenging dihydro-3-nitronaphthalenes using one equivalent of phosphoramidite ligand to rhodium catalyst. A concise formal asymmetric synthesis of the dopamine D1 agonist, dihydrexidine was accomplished using the method.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ea0423cfb12f0bbd79a4021cd1413d7b https://doi.org/10.1002/adsc.201200241 Zobrazit plný text záznamu Plný text ve formátu PDF