Remineralization of natural early caries lesions in vitro by P11-4 monitored with photothermal radiometry and luminescence
| Autor: | Koneswaran Sivagurunathan, Bonny P. Y. Wong, Jennifer Kirkham, Joshua D. Silvertown, Stephen H. Abrams, Bennett T. Amaechi |
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| Rok vydání: | 2017 |
| Předmět: |
Saliva
Remineralisation Enamel paint Chemistry business.industry Dentistry 030206 dentistry General Medicine 01 natural sciences Placebo group In vitro 010309 optics stomatognathic diseases 03 medical and health sciences 0302 clinical medicine stomatognathic system visual_art 0103 physical sciences Photothermal radiometry visual_art.visual_art_medium Luminescence Nuclear medicine business |
| Zdroj: | Journal of Investigative and Clinical Dentistry. 8:e12257 |
| ISSN: | 2041-1618 |
| DOI: | 10.1111/jicd.12257 |
| Popis: | Aim: The efficacy of self-assembling peptide P11 -4 to regenerate enamel in natural early caries lesions was evaluated over 50 days by photothermal radiometry and luminescence using The Canary System (CS) and The Canary Lab (CL). Methods: Baseline readings for sound and carious sites on smooth surfaces of extracted teeth were obtained by scanning with CS and CL. Teeth were then randomly assigned to a treatment group (TG, treated with P11 -4), a placebo group (PG, same vehicle as treatment group without P11 -4), or a control group (CG, no treatment). All the teeth were then placed in artificial saliva to facilitate natural remineralization, and the sites were rescanned with CS and CL at 7, 14, 30, and 50 days. Results: For carious sites in TG, mean canary numbers (CN) derived from CS decreased significantly (P |
| Databáze: | OpenAIRE |
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