The Effect of Ligand Binding on the FTIR Spectra of Serine Proteinase Enzymes
| Autor: | M. J. Blackler, M. P. Weir, C. W. Wharton |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Drug
chemistry.chemical_classification media_common.quotation_subject Ftir spectra Serine Enzyme Thrombin chemistry Biochemistry Antithrombotic medicine Protein secondary structure circulatory and respiratory physiology media_common medicine.drug Discovery and development of direct thrombin inhibitors |
| Zdroj: | Spectroscopy of Biological Molecules ISBN: 9789401041669 |
| Popis: | Thrombin has been extensively studied due to its role in thrombosis and other diseases [1]. Thrombin inhibitors might prove to be effective antithrombotic drugs [2]. Knowledge of how thrombin inhibitors bind to thrombin allows the possibility of structure-based drug design [2]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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