Le diagnostic histologique de la maladie cœliaque
| Autor: | N. Brousse, V. Verkarre |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
education.field_of_study medicine.diagnostic_test business.industry Population nutritional and metabolic diseases General Medicine medicine.disease digestive system Gastroenterology digestive system diseases Coeliac disease Surgery Lymphoma Internal medicine Biopsy medicine Enteropathy-associated T-cell lymphoma Sampling (medicine) Villous atrophy education business Pathological |
| Zdroj: | Pathologie Biologie. 61:e13-e19 |
| ISSN: | 0369-8114 |
| Popis: | Coeliac disease is a common disease, affecting 1% of the population. Clinical manifestations are multiple. The diagnosis requires serologic testing and a duodenal biopsy that shows the characteristic findings of intraepithelial lymphocytosis, crypt hyperplasia and villous atrophy, and a positive response to a gluten-free diet. In most patients, the histological diagnosis is easily established. Pitfalls in the pathological diagnosis include a poorly orientated biopsy specimen, either an inadequate biopsy sampling in patients with patchy villous atrophy and the other causes of villous atrophy. A non-response to the gluten-free diet needs to reassess first, the initial diagnosis, second to be sure of the gluten-free diet adherence, and third, to exclude malignant complications such as refractory celiac disease or enteropathy-associated T-cell lymphoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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