IMMUNOLOGY AND PROSPECTS OF IMMUNOTHERAPY OF THE PRIMARY MALIGNANT BRAIN TUMORS: CELLULAR THERAPY, VIROTHERAPY

Autor: Svetlana Kuleva, Aleksandr Druy
Rok vydání: 2020
Předmět:
Zdroj: Problems in oncology. 66:218-222
ISSN: 0507-3758
DOI: 10.37469/0507-3758-2020-66-3-218-222
Popis: High-grade gliomas (Grade III-IV) are aggressive brain tumor with poor prognosis. Recent investigations are aimed on pathogenic mechanisms of tumor growth on cellular at the molecular-genetic level for the development of effective individualized treatment methods, while the limit of survival benefit of conventional therapeutic options has been already reached. Integration of immunotherapeutic approach (cellular therapy, virotherapy) into treatment schemes of the brain tumors is relevant and promising strategy based on biological features of tumor tissue.
Databáze: OpenAIRE