An organocatalytic C–C bond cleavage approach: a metal-free and peroxide-free facile method for the synthesis of amide derivatives

Autor:	Raghuram Gujjarappa, Dhananjaya Kaldhi, Vanaparthi Satheesh, Saibabu Polina, Nagaraju Vodnala, Chandi C. Malakar, Arup K. Kabi
Rok vydání:	2020
Předmět:	Reaction conditions chemistry.chemical_compound Chemistry Amide Materials Chemistry General Chemistry Cleavage (embryo) Combinatorial chemistry Peroxide Catalysis Bond cleavage
Zdroj:	New Journal of Chemistry. 44:20940-20944
ISSN:	1369-9261 1144-0546
Popis:	A facile organocatalytic approach has been devised towards the synthesis of amide derivatives using 1,3-dicarbonyls as easily available acyl-sources under peroxide-free reaction conditions. This transformation was accomplished by the cleavage of the C–C bond in the presence of TEMPO as an organocatalyst and excludes the use of transition-metals and harsh reaction conditions. A broad range of substrates with diverse functional groups were well tolerated and delivered the products in high yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e9a5929f67a7c7e3862689fbb358d57a https://doi.org/10.1039/d0nj04158k Zobrazit plný text záznamu