Immune Checkpoint Inhibitors in the Curative Setting: Pre-clinical and Clinical Data
| Autor: | Simon Beyaert, Natasha Honoré, Jean-Pascal Machiels |
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| Rok vydání: | 2023 |
| Zdroj: | Critical Issues in Head and Neck Oncology ISBN: 9783031231742 |
| DOI: | 10.1007/978-3-031-23175-9_11 |
| Popis: | Pembrolizumab and nivolumab, two monoclonal antibodies (mAbs) targeting programmed cell death protein-1 (PD-1), improve the overall survival of patients with inoperable recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). For curable HNSCC, the role of immunotherapy is under investigation. In this chapter, we briefly review the current use of immunotherapy with surgery or radio(chemo)therapy in the treatment of HNSCC with curative intent. |
| Databáze: | OpenAIRE |
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