Hypericum Treatment of Mild Depressions with Somatic Symptoms

Autor:	W.-D. Hübner, S. Lande, H. Podzuweit
Rok vydání:	1994
Předmět:	03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine 030214 geriatrics Neurology (clinical) Geriatrics and Gerontology 030217 neurology & neurosurgery
Zdroj:	Journal of Geriatric Psychiatry and Neurology. 7:12-14
ISSN:	1552-5708 0891-9887
DOI:	10.1177/089198879400701s05
Popis:	In a randomized, placebo-controlled, double-blind study, 39 patients with depression with somatic symptoms were treated with hypericum extract LI 160. The therapy lasted for 4 weeks; the dosage was 300 mg three times daily. At the onset of the study as well as after 2 and 4 weeks, the following criteria were analyzed: HAMD, B-L, CGI, and vegetative symptoms. The results show a significant improvement in the active treatment group at the 5% level as compared to placebo. Seventy percent of the patients treated with LI 160 were free of symptoms after 4 weeks. Typical symptoms of the depression such as lack of activity, tiredness, fatigue, and disturbed sleep, were especially responsive. In no case were any undesirable side effects observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e978be9e2b7da3636b8984f5c4954439 https://doi.org/10.1177/089198879400701s05 Zobrazit plný text záznamu