Gene Selection Based on Support Vector Machine using Bootstrap

Autor: Ja-Yong Koo, Kyoung-Hee Kim, Seuck-Heun Song, Chang-Yi Park
Rok vydání: 2007
Předmět:
Zdroj: Korean Journal of Applied Statistics. 20:531-540
ISSN: 1225-066X
DOI: 10.5351/kjas.2007.20.3.531
Popis: The recursive feature elimination for support vector machine is known to be useful in selecting relevant genes. Since the criterion for choosing relevant genes is the absolute value of a coefficient, the recursive feature elimination may suffer from a scaling problem. We propose a modified version of the recursive feature elimination algorithm using bootstrap. In our method, the criterion for determining relevant genes is the absolute value of a coefficient divided by its standard error, which accounts for statistical variability of the coefficient. Through numerical examples, we illustrate that our method is effective in gene selection.
Databáze: OpenAIRE