Synthesis of (R,R)- and (S,S)-Norphos

Autor: Manfred Muschiol, Henri Brunner, Manfred Zabel
Rok vydání: 2008
Předmět:
Zdroj: Synthesis. 2008:405-408
ISSN: 1437-210X
0039-7881
DOI: 10.1055/s-2008-1032133
Popis: Oxidation of ( E)-1,2-bis(diphenylphosphanyl)ethene with hydrogen peroxide gave ( E)-1,2-bis(diphenylphosphoryl)ethene. Diels-Alder reaction of ( E)-1,2-bis(diphenylphosphoryl)ethene with cyclopentadiene yielded 2,3-bis(diphenyl--phosphoryl)bicyclo[2.2.1]hept-5-ene (NorphosO). RAC-NorphosO was resolved with O, O-dibenzoyltartaric acid. ( R, R)- and ( S, S)-NorphosO were reduced with trichlorosilane to give 2,3-bis(diphen-ylphosphanyl)bicyclo[2.2.1]hept-5-ene [( R, R)- and ( S, S)-Norphos].
Databáze: OpenAIRE
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