Efficient synthesis of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides

Autor:	M. Teresa Aranda, Esteban Dominguez, Jose Luis Garcia Ruano, Jesús de Blas, M. Carmen Carreño, Miriam del Prado
Rok vydání:	2000
Předmět:	chemistry.chemical_compound chemistry Nucleophile Benzothiadiazine Organic Chemistry Drug Discovery chemistry.chemical_element Organic chemistry Biochemistry Carbon Carbanion
Zdroj:	Tetrahedron Letters. 41:9825-9828
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)01779-2
Popis:	A simple method for the preparation of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides is described. Treatment of N-sulfonyl ketimines 2 and 3 with different carbon nucleophiles afforded the corresponding of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 1 in isolated yields of 35–84%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e9470225c444a0a61f087b4012d1eeb0 https://doi.org/10.1016/s0040-4039(00)01779-2 Zobrazit plný text záznamu Full Text from ScienceDirect