Lung Transplantation in Russian Federation

Autor: S. N. Avdeev, A. G. Chuchalin, S.V. Golovinskiy, D.H. Tsurova, A.A. Romanov, E.A. Tarabrin, E.I. Pervakova, N. A. Karchevskaya, M.S. Hubutiy, O.A. Kurilova, A. M. Gasanov, M.M. Abakumov
Rok vydání: 2014
Předmět:
Zdroj: The Journal of Heart and Lung Transplantation. 33:S263-S264
ISSN: 1053-2498
DOI: 10.1016/j.healun.2014.01.694
Popis: s S263 Results: Overall, 11 pts (55%) have died (7 in-hospital mortality, 4 late-mortality). 50% of the overall pts. had an INTERMACS 4 score and the remaining pts were of lower INTERMACS score, while there was no difference in the score between the surviving and expired pts. Of the relevant pre-op parameters, there was no significant difference between the survival groups: RV function was generally slightly decreased (FAC 21±10% vs 30±13%, TAPSE 1,5±0,4 cm vs 1.3±0.5 cm, alive vs expired, NS), the cardiac index was low (1.7±0.5 L/min/m2 vs 1.8±0.5 L/min/m2, alive vs expired, NS), TPG values were borderline (13±5.3 mmHg vs 12.6±8.3 mmHg, alive vs expired, NS) and PVR was moderately elevated (3.7±1.4 WU vs 3.2±2.6 WU, alive vs expired, NS). Preoperative data significantly differed only in the platelet count being lower in the expired pts (250±64x103/mm3 vs. 154±65x103/ mm3, p< 0.01). Significantly higher post-implant PVR was found in the expired compared to the living pts (3.8±2.8 WU vs. 1.8±0.4 WU, p< 0.05). Notably, all of the expired pts had a significant increase in postoperative PVR values (0.59±0.25 WU), while it was decreased in all but one of the surviving pts (2.02±1.74 WU, p= 0.02). Conclusion: These preliminary data show that there is no significant difference in predictors of survival among our patients with a generally low INTERMACS score, apart from a low platelet count. However, there is a clear increase in postoperative PVR values in the expired pts, which warrants further investigation.
Databáze: OpenAIRE