Decreased dopamine D2receptor binding in essential blepharospasm

Autor:	Manabu Mochizuki, Kiichi Ishiwata, Motohiro Kiyosawa, Masato Wakakura, Yukihisa Suzuki, Keiichi Oda, Kenji Ishii, Chiharu Horie
Rok vydání:	2009
Předmět:	Raclopride medicine.medical_specialty business.industry Eye disease Putamen Blepharospasm General Medicine Striatum medicine.disease eye diseases Endocrinology Neurology Dopamine Internal medicine Dopamine receptor D2 medicine Neurology (clinical) medicine.symptom Receptor business medicine.drug
Zdroj:	Acta Neurologica Scandinavica. 119:49-54
ISSN:	1600-0404 0001-6314
DOI:	10.1111/j.1600-0404.2008.01053.x
Popis:	Objectives – The purpose of this study was to investigate whether dopamine D2 receptor binding was altered in the striatum of essential blepharospasm patients. Methods – Striatal dopamine D2 receptor binding was measured with positron emission tomography and [11C]raclopride. We studied eight drug-naive patients with bilateral blepharospasm and eight age-matched normal controls. Results – The uptake indices in the blepharospasm group were significantly reduced by 11.7% in the caudate (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e934f48ea8e5b94f4580f0376a737007 https://doi.org/10.1111/j.1600-0404.2008.01053.x Zobrazit plný text záznamu Plný text ve formátu PDF