Non‐invasive left ventricular myocardial work indices in healthy adolescents at rest
| Autor: | Garick D. Hill, Anna Mullikin, Wojciech Mazur, Vien T. Truong, Michael D. Taylor, Sarah Pradhan, Andrew N. Redington, Justin T. Tretter |
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| Rok vydání: | 2021 |
| Předmět: |
Body surface area
medicine.medical_specialty Supine position Ejection fraction business.industry Speckle tracking echocardiography 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Blood pressure Internal medicine Heart rate medicine Cardiology Radiology Nuclear Medicine and imaging 030212 general & internal medicine Derivation Cardiology and Cardiovascular Medicine business Cardiac imaging |
| Zdroj: | The International Journal of Cardiovascular Imaging. 37:2429-2438 |
| ISSN: | 1573-0743 1569-5794 |
| DOI: | 10.1007/s10554-021-02218-y |
| Popis: | Global myocardial work (GMW) provides a metric of left ventricular (LV) function and energy consumption. Its non-invasive assessment by echocardiography correlates with invasive measures and normal values have been reported in healthy adults. We aimed to establish normal values in a healthy adolescent population. Fifty-two healthy adolescents (mean age = 14.5 ± 2.0 years, range 11–19 years, 62% male) with normal echocardiograms were included. Brachial cuff blood pressure was obtained immediately following apical imaging in the supine position. Post-processing of echocardiograms for speckle tracking strain measurement and derivation of global myocardial work indices from LV pressure–strain loops was performed. The mean global work index (GWI) was 1802.0 ± 264.4 mmHg% with mean global work efficiency of 95.5 ± 1.1%. The mean global constructive work (GCW) was 2054.5 ± 297.3 mmHg%, and the mean global wasted work 83.8 ± 28.1 mmHg%. On multivariable analysis, there were significant associations between both GWI and GCW with systolic blood pressure (β coefficient = 0.57, p |
| Databáze: | OpenAIRE |
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