A Hetero Pauson-Khand Reaction of Ketenimines: A New Synthetic Method for γ-Exomethylene-α,β-unsaturated γ-Lactams

Autor:	Katsuya Sugizaki, Takashi Otani, Noriki Kutsumura, Takao Saito, Hiroyuki Osada
Rok vydání:	2010
Předmět:	Pharmacology chemistry.chemical_compound Chemistry Dimethyl sulfoxide Pauson–Khand reaction Organic Chemistry Medicinal chemistry Toluene Cycloaddition Analytical Chemistry Ketenimine
Zdroj:	HETEROCYCLES. 80:207
ISSN:	0385-5414
DOI:	10.3987/com-09-s(s)62
Popis:	A novel ketenimine Pauson-Khand reaction has been described for the first time. C,C,N-Triarylketenimines reacted with alkyne-dicobalthexacarbonyl complexes upon heating in toluene in the presence of dimethyl sulfoxide as a promoter to afford γ-lactams, 5-(diphenylmethylene)-1H-pyrrol-2(5H)-ones, in good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e91c81541a073d0a6e7430ca174df0ff https://doi.org/10.3987/com-09-s(s)62 Zobrazit plný text záznamu